Brand-name GLP-1s online: the manufacturer floors and the platforms above them
Updated 2026-08-10 · figures captured 2026-08-09 · how we verify
The brand lane has a floor and a stack. The floor is manufacturer-direct: LillyDirect↗ sells Zepbound single-dose vials to cash payers at $299 (2.5 mg), $399 (5 mg), and $449 (7.5–15 mg) — the maintenance price conditional on refilling within 45 days; NovoCare↗ sells Wegovy at $349 standard with a $199 two-month intro at starter doses, and the oral Wegovy pill from $149. Those are the numbers every platform above them should be measured against.
The stack is telehealth on top of brand product: Ro ($145/mo membership; prescribing, monitoring, insurance work; medication billed separately), Hims & Hers↗ (bundled brand programs after its pivot from compounding), WeightWatchers Clinic↗ ($74/mo with behavioral program), plus clinical-heavy options (Calibrate, Form Health↗) and generalist telehealth (PlushCare↗, Sesame). Each layer is worth exactly what its services are worth to you — the medication underneath is identical, and its floor price is public. Records for all of them: below and at /providers/.
RANK01
LillyDirect (Zepbound)
No membership fee; shipping included; names its pharmacy network.
SOURCE-VERIFIED · captured 2026-08-09 · source
$449/MO ALL-IN
RANK02
NovoCare Pharmacy (Wegovy)
Dose-flat — the maintenance price equals the starter price; no membership fee; shipping included.
SOURCE-VERIFIED · captured 2026-08-10 · source
$349/MO ALL-IN
RANK05
WeightWatchers Clinic
$74/mo membership already inside the figure; names its pharmacy network.
—/MO ALL-IN
Compounded programs are the other lane entirely — not FDA-approved product, cash-only, ranked at cheapest GLP-1 providers — and this page's platforms are precisely the ones that left that lane or never entered it.
The leaders, across a full year
Monthly figures flatter everyone equally; a year separates them. The field, annualized on the same all-in basis: LillyDirect (Zepbound): $5,388 monthly-billed.
Spread top-to-bottom within just these five: $0 a year — before considering the rest of the field, where the verified ceiling reaches $5,388. Prepaid paths shrink the totals and add commitment; the trade is priced properly in the annual-cost analysis and at your own numbers in the calculator.
Structure census across the 1 priced programs above: 0 are dose-flat, 1 carry no membership, 1 name their pharmacy network, and 0 publish a prepaid path below their own monthly-billed year. Those four counts are the shape of this list — the price column tells you what a program charges; the census tells you what kind of thing it is.
How to use a list like this well: shortlist two or three, pull each provider page, and read the record — structure, exit terms, pharmacy transparency, evidence flags — before letting the price column decide. The ranking gets you to the right neighborhood; the records keep you out of the wrong house.
Frequently asked
What is the cheapest option on this list?
LillyDirect (Zepbound) at $449 per month all-in on the maintenance basis, captured 2026-08-09. Every figure here is medication plus mandatory fees; confirm at the provider's checkout before enrolling.
How is this ranking produced?
By sorting the public dataset on verified all-in monthly price at the maintenance dose — no editorial reordering, no paid placement. Basis, exclusions, and verification cycle: /methodology/; recompute it yourself from the JSON.
Are compounded GLP-1s on this page FDA-approved?
No compounded product is FDA-approved. Since 2025 compounded tirzepatide and semaglutide are limited to patient-specific 503A prescriptions with documented clinical need; brand options (Zepbound, Wegovy) are the approved products. Regulatory timeline: here.