Fifty 410 vs LillyDirect (Zepbound) (2026): prices, structure, verdict
On tirzepatide, only LillyDirect (Zepbound)↗ has a rankable figure: $449 a month all-in; Fifty 410↗ publishes no maintenance-dose tirzepatide figure we could capture (advertised start: $133), so a like-for-like number does not exist.
Updated 2026-08-10 · figures captured 2026-08-09 · how we verify
Fifty 410
- Tirzepatide all-in
- from $133 · no maintenance figure
- Semaglutide all-in
- not offered
- 12-mo tirzepatide (best path)
- —
- Membership
- none
- Shipping
- unknown
- Commitment
- unknown
- Cancellation
- not published
- Pharmacy
- not named
- States
- not published
- Insurance
- no
- Evidence
- source-verified · 2026-08-05
LillyDirect (Zepbound)
- Tirzepatide all-in
- $449/mo
- Semaglutide all-in
- not offered
- 12-mo tirzepatide (best path)
- $5,388
- Membership
- none
- Shipping
- included (or same-day retail pickup)
- Commitment
- 45-day refill cadence to keep pricing
- Cancellation
- no subscription; refill-window rules apply
- Pharmacy
- ✔ Eli Lilly direct / retail partners
- States
- 50 states
- Insurance
- no
- Evidence
- source-verified · 2026-08-09
The two records, condensed
Fifty 410: the record, condensed
On tirzepatide, Fifty 410 advertises from $133 — and publishes no maintenance-dose figure we could capture. A starter-only price cannot be annualized, cannot be ranked, and should be treated as the bottom of an unstated range: before enrolling on its strength, get the 10 mg price in writing, and if the program will not state it, price the program at its ceiling rather than its floor.
Operationally at Fifty 410: shipping unknown; commitment unknown; cancellation not published; pharmacy not publicly named — ask in writing before paying; states: not published; evidence source-verified, captured 2026-08-05. The full record with source and archive links: the Fifty 410 page · visit Fifty 410 ↗
LillyDirect (Zepbound): the record, condensed
LillyDirect (Zepbound)’s tirzepatide program bills $449 a month once every mandatory fee is counted, measured at the 10 mg maintenance basis. Pricing steps with the dose here: from $299 at entry to $449 at the 10 mg basis. Multiply the wrong one of those by twelve and your budget is off by $1,800 a year, which is why every ranking on this site uses the larger number.
The absence worth noticing: no mandatory membership. Across this index memberships run $25–$145 a month and hide outside headline prices; here the headline is the bill.
Context for that figure: it ranks #0 of 17 in the verified tirzepatide index — $234/month above the floor (NexLife↗, $215) — and sits $0 over the brand benchmark (Zepbound (LillyDirect), $449 at maintenance). Annualized, a monthly-billed year here runs $5,388.
Operationally at LillyDirect (Zepbound): shipping included (or same-day retail pickup); commitment 45-day refill cadence to keep pricing; cancellation no subscription; refill-window rules apply; pharmacy named (Eli Lilly direct / retail partners); states: 50 states; evidence source-verified, captured 2026-08-09. The full record with source and archive links: the LillyDirect (Zepbound) page · visit LillyDirect (Zepbound) ↗
Everything besides the price
Coverage: Fifty 410 publishes “not published”; LillyDirect (Zepbound) publishes “50 states” — for anything short of an explicit 50-state claim, intake is the final word.
Pharmacy transparency splits them: LillyDirect (Zepbound) names its network (Eli Lilly direct / retail partners); Fifty 410 does not, which shifts the burden of verification onto your intake questions.
Exit terms: Fifty 410 — unknown; not published. LillyDirect (Zepbound) — 45-day refill cadence to keep pricing; no subscription; refill-window rules apply.
Evidence: Fifty 410 source-verified (captured 2026-08-05); LillyDirect (Zepbound) source-verified (2026-08-09).
A rule that has held across this index: disclosure predicts disclosure. Whichever of these two publishes more — pharmacies, states, exit terms — is usually the one whose invoice matches its ad.
Switching between Fifty 410 and LillyDirect (Zepbound)
Prescriptions do not transfer like phone numbers: moving in either direction means completing the destination’s intake and having its prescriber write a new patient-specific prescription. The mechanics that prevent a bad month: confirm the destination serves your state and quotes your current dose in writing before cancelling anything; time the first new shipment to overlap the last old one rather than gap it; cancel the origin per its published terms (Fifty 410: not published; LillyDirect (Zepbound): no subscription; refill-window rules apply) and screenshot the confirmation; and never leave a prepaid balance stranded — which is the standing argument for prepaying only after a program has already earned a few monthly cycles.
Which one, for whom
Cheapest tirzepatide month-to-month: LillyDirect (Zepbound) ($449).
Cheapest 12-month path: LillyDirect (Zepbound) at $5,388 (monthly billing).
Pharmacy transparency: LillyDirect (Zepbound) names its fulfillment (Eli Lilly direct / retail partners); Fifty 410 does not.
Where a like-for-like price does not exist, the comparison becomes a disclosure contest: the program that answers the pharmacy, states, and maintenance-price questions plainly is the one whose other claims deserve weight.
Verdicts are computed from the records above — recompute them from the dataset. Full profiles: Fifty 410 · LillyDirect (Zepbound).
Frequently asked
Which is cheaper, Fifty 410 or LillyDirect (Zepbound)?
On tirzepatide, only LillyDirect (Zepbound) has a rankable figure: $449 a month all-in ; Fifty 410 publishes no maintenance-dose tirzepatide figure we could capture (advertised start: $133), so a like-for-like number does not exist.
Is there a membership fee at Fifty 410 or LillyDirect (Zepbound)?
Fifty 410: none. LillyDirect (Zepbound): none.
Where do these numbers come from?
From each provider's own published pages, captured 2026-08-05 (Fifty 410) and 2026-08-09 (LillyDirect (Zepbound)), normalized to the all-in maintenance basis and archived. Full records: the provider pages and the public dataset.
Is Fifty 410 or LillyDirect (Zepbound) dose-flat?
Fifty 410: no flat structure verified — get the maintenance-dose price in writing. LillyDirect (Zepbound): no — assume the advertised figure is a starter price until the maintenance number is stated. Flat pricing turns the advertised number into a ceiling; tiered pricing makes it a floor.
Can I check both Fifty 410 and LillyDirect (Zepbound) against their sources?
Yes — that is the design. Each record carries a capture date (2026-08-05 / 2026-08-09), a source link, and an archive link in the database; the figures on this page regenerate from those records, so any discrepancy you find is reportable and fixable sitewide in one pass.
What states do Fifty 410 and LillyDirect (Zepbound) serve?
Fifty 410: not published. LillyDirect (Zepbound): 50 states. Telehealth availability rides on clinician licensure and pharmacy permits, so for anything short of an explicit 50-state claim the enrollment flow is the final word; the state-by-state index adds the known exceptions.
Is shipping included at Fifty 410 and LillyDirect (Zepbound)?
Fifty 410: unknown. LillyDirect (Zepbound): included (or same-day retail pickup). Cold-chain delivery is a real cost; programs that fold it into the all-in figure remove a checkout surprise, and any separate shipping line belongs in your comparison math before the prices above are treated as equivalent.
Which is more transparent, Fifty 410 or LillyDirect (Zepbound)?
On the checkable axes: pharmacy named — Fifty 410 no, LillyDirect (Zepbound) yes (Eli Lilly direct / retail partners); state list — Fifty 410 published, LillyDirect (Zepbound) published; cancellation terms — Fifty 410 published, LillyDirect (Zepbound) published; evidence — source-verified vs source-verified. Disclosure predicts disclosure in this market, and the axis where one of these two goes quiet is usually where your intake questions should get loud.