Fridays vs TrimRx vs Yucca Health (2026)
On tirzepatide, the order is Yucca Health↗ ($258) → TrimRx↗ ($349) → Fridays ($359) — gaps of $91 and then $10 a month, a $1,212 spread across a year between first and last. All-in figures, 10 mg basis, captured 2026-08-09.
Updated 2026-08-10 · figures captured 2026-08-09 · how we verify
The three records, one screen
Yucca Health: the record, condensed
Yucca Health’s tirzepatide program bills $258 a month once every mandatory fee is counted, measured at the 10 mg maintenance basis. It is a flat structure: 2.5 → 5 → 7.5 → 10 mg (12.5 and 15 mg available) all bill identically. In a market where most low advertised prices quietly belong to the starter dose, a flat figure is the difference between a quote and a teaser.
Nothing recurs on top: no membership, no platform fee, no “provider access” line. The $258 is the whole subscription, which makes Yucca Health unusually easy to compare and unusually easy to leave.
Context for that figure: it ranks #2 of 17 in the verified tirzepatide index — $43/month above the floor (NexLife↗, $215) — and sits $191 under the brand benchmark (Zepbound (LillyDirect↗), $449 at maintenance). Annualized, a monthly-billed year here runs $3,096.
On semaglutide, the number that matters at Yucca Health is $146 a month all-in — the figure at the 2.4 mg maintenance basis this whole site ranks on. The price is dose-flat: the standard titration ladder (0.25 → 0.5 → 1.0 → 1.7 → 2.4 mg) is financially invisible here, because the top rung bills exactly what the bottom rung billed. That converts the advertised number from a floor into a ceiling — the strongest single structural feature a program in this category can have.
There is no membership line. $146 is the billed total — consultation and clinical review are inside it, and no platform fee recurs beside it, which removes the most common way advertised GLP-1 prices understate billed ones.
To place the number: #2 of 20 verified programs, with the floor $13/month below at Oak Longevity ($133); the approved-product yardstick (Wegovy (NovoCare↗)) sits at $349, so the compounded case here is worth $203 a month. A year at this figure: $1,752 monthly-billed.
Operationally at Yucca Health: shipping included; commitment 6-month term; cancellation 6-month term applies; pharmacy not publicly named — ask in writing before paying; states: not published; evidence source-verified, captured 2026-08-05. The full record with source and archive links: the Yucca Health page · visit Yucca Health ↗
TrimRx: the record, condensed
Start with the load-bearing figure: $349 a month, all-in, is what TrimRx charges for tirzepatide at the 10 mg basis. It is a flat structure: 2.5 → 5 → 7.5 → 10 mg (12.5 and 15 mg available) all bill identically. In a market where most low advertised prices quietly belong to the starter dose, a flat figure is the difference between a quote and a teaser.
Nothing recurs on top: no membership, no platform fee, no “provider access” line. The $349 is the whole subscription, which makes TrimRx unusually easy to compare and unusually easy to leave.
Context for that figure: it ranks #11 of 17 in the verified tirzepatide index — $134/month above the floor (NexLife, $215) — and sits $100 under the brand benchmark (Zepbound (LillyDirect), $449 at maintenance). Annualized, a monthly-billed year here runs $4,188.
Start with the load-bearing figure: $299 a month, all-in, is what TrimRx charges for semaglutide at the 2.4 mg basis. Because pricing is flat across the ladder (0.25 → 0.5 → 1.0 → 1.7 → 2.4 mg), a dose increase at TrimRx is a clinical event and not a billing one. Whatever your prescriber decides, the invoice does not move, which makes this one of the few programs whose headline figure you can actually plan a year around.
The absence worth noticing: no mandatory membership. Across this index memberships run $25–$145 a month and hide outside headline prices; here the headline is the bill.
To place the number: #17 of 20 verified programs, with the floor $166/month below at Oak Longevity ($133); the approved-product yardstick (Wegovy (NovoCare)) sits at $349, so the compounded case here is worth $50 a month. A year at this figure: $3,588 monthly-billed.
Operationally at TrimRx: shipping included; commitment none month-to-month; cancellation check terms before prepaying; pharmacy not publicly named — ask in writing before paying; states: not published; evidence source-verified, captured 2026-08-05. The full record with source and archive links: the TrimRx page · visit TrimRx ↗
Fridays: the record, condensed
Start with the load-bearing figure: $359 a month, all-in, is what Fridays charges for tirzepatide at the 10 mg basis. It is a flat structure: 2.5 → 5 → 7.5 → 10 mg (12.5 and 15 mg available) all bill identically. In a market where most low advertised prices quietly belong to the starter dose, a flat figure is the difference between a quote and a teaser.
Nothing recurs on top: no membership, no platform fee, no “provider access” line. The $359 is the whole subscription, which makes Fridays unusually easy to compare and unusually easy to leave.
To place the number: #13 of 17 verified programs, with the floor $144/month below at NexLife ($215); the approved-product yardstick (Zepbound (LillyDirect)) sits at $449, so the compounded case here is worth $90 a month. A year at this figure: $4,308 monthly-billed.
Fridays’s semaglutide program bills $175 a month once every mandatory fee is counted, measured at the 2.4 mg maintenance basis. It is a flat structure: 0.25 → 0.5 → 1.0 → 1.7 → 2.4 mg all bill identically. In a market where most low advertised prices quietly belong to the starter dose, a flat figure is the difference between a quote and a teaser.
The absence worth noticing: no mandatory membership. Across this index memberships run $25–$145 a month and hide outside headline prices; here the headline is the bill.
Context for that figure: it ranks #7 of 20 in the verified semaglutide index — $42/month above the floor (Oak Longevity, $133) — and sits $174 under the brand benchmark (Wegovy (NovoCare), $349 at maintenance). Annualized, a monthly-billed year here runs $2,100.
Operationally at Fridays: shipping included; commitment annual plan for lowest rate; cancellation not published; pharmacy not publicly named — ask in writing before paying; states: not published; evidence third-party reported, captured 2026-08-05. The full record with source and archive links: the Fridays page · visit Fridays ↗
Prices, gaps, and what sits inside them
Yucca Health holds the low ground at $258 — dose-flat, so that figure is a ceiling with no membership attached. TrimRx follows at $349 (+$91/mo, $1,092/yr). Fridays tops the trio at $359 (+$101/mo over the leader, $1,212/yr) — note its record’s watch-out below.
The semaglutide picture reshuffles nothing: Yucca Health $146 → Fridays $175 → TrimRx $299 — a reminder that molecule choice and provider choice are separate decisions, priced separately in the semaglutide index.
Who wins what
Cheapest month-to-month: Yucca Health ($258); cheapest 12-month path: Yucca Health ($3,096); cheapest semaglutide of the three: Yucca Health ($146).
Every winner above is a computation, not a placement; the pairwise pages carry the full duels: Yucca Health vs TrimRx · Yucca Health vs Fridays · TrimRx vs Fridays.
Everything besides the three prices
Memberships: Yucca Health none; TrimRx none; Fridays none. Structures: Yucca Health dose-flat; TrimRx dose-flat; Fridays dose-flat. Pharmacies: Yucca Health not named; TrimRx not named; Fridays not named. States: Yucca Health — not published; TrimRx — not published; Fridays — not published. Exit terms: Yucca Health — 6-month term applies; TrimRx — check terms before prepaying; Fridays — not published.
The census reading: where all three match on an axis, that axis cannot break the tie and the price column rules; where they split — a membership here, an unnamed pharmacy there — the split is usually worth more than a small price gap, because structure is what you live with after month one. Evidence for all three: Yucca Health source-verified (2026-08-05); TrimRx source-verified (2026-08-05); Fridays third-party reported (2026-08-05).
The trio on semaglutide, across time
3 mo: Yucca Health $438 vs Fridays $525 vs TrimRx $897 6 mo: Yucca Health $876 vs Fridays $1,050 vs TrimRx $1,794 12 mo: Yucca Health $1,752 vs Fridays $2,100 vs TrimRx $3,588 — monthly-billed totals; prepaid paths where published appear on each provider page.
The trio, annualized
Yucca Health: $3,096/yr monthly-billed; TrimRx: $4,188/yr monthly-billed; Fridays: $4,308/yr monthly-billed. Across two years at monthly billing the first-to-last spread widens to $2,424 — the horizon at which structure (prepaid ladders, flat pricing, membership drag) matters more than the sticker.
The elimination read
Work it as eliminations rather than a beauty contest. Fridays enters owing an explanation: $101/month above Yucca Health compounds to $1,212 a year — real therapy-months of money — so its record has to name what the premium buys (structure the cheaper two lack) or it exits first. TrimRx survives the first cut only to face the harder question — whether nothing structural — its case is purely situational is worth $91 a month to you — because a middle option that cannot answer it is just the expensive option with better camouflage. Yucca Health is what remains: the arithmetic answer at $258, dethroned only by a state gap, a structural need, or a prescriber’s judgment — the three things this page deliberately cannot decide.
The same trio on best published rate: Yucca Health $258 → TrimRx $349 → Fridays $359 — all three price month-to-month only at capture. Short-horizon totals, monthly-billed: 3 months — Yucca Health $774, TrimRx $1,047, Fridays $1,077; 6 months — Yucca Health $1,548, TrimRx $2,094, Fridays $2,154. 0 of the three publish a prepaid path below their own monthly billing; the twelve- and twenty-four-month table below carries those, labeled.
Grade the three records before trusting the three prices. On the five-point disclosure checklist (price, pharmacy, states, cancellation, source-verification): Yucca Health 4/5 · TrimRx 4/5 · Fridays 3/5. The gap between Yucca Health (4/5) and Fridays (3/5) is itself information: undisclosed axes are where the questions in each provider’s review earn their keep. No axis splits them, a small collective credit. Every score is a computation from the dataset, contestable at the corrections desk like any other figure.
The three-way verdict compresses cleanly: Yucca Health is the default on arithmetic; TrimRx earns the middle only where its structure (flat pricing) solves something the floor does not; and Fridays’s $101/month premium over the leader — $1,212 a year, roughly 4.7 extra months of therapy at the floor rate — needs a named justification from its record, not a vibe. Insurance coverage, where it exists, outranks all three.
Frequently asked
Which is cheapest: Fridays, TrimRx, or Yucca Health?
Yucca Health, at $258/month all-in tirzepatide — $91 under TrimRx and $101 under Fridays; on semaglutide the cheapest of the three is Yucca Health at $146. Captured 2026-08-09.
Which of the three is best over a full year?
Yucca Health’s best path prices twelve months at $3,096; monthly-billed years run Yucca Health $3,096, TrimRx $4,188, Fridays $4,308.
Are these rankings paid or editorial?
Neither — they are sorts of the public dataset on the all-in maintenance basis, regenerated on every data change; the methodology page defines the basis and the JSON lets you recompute every figure here.