ShedRx vs SkinnyRx (2026): prices, structure, verdict

On tirzepatide, ShedRx↗ is cheaper: $289 versus $299 a month all-in — a $10 monthly gap, $120 across a year of maintenance dosing.

Updated 2026-08-10 · figures captured 2026-08-09 · how we verify

On semaglutide, SkinnyRx↗ is cheaper: $199 versus $249 a month all-in — a $50 monthly gap, $600 across a year of maintenance dosing, and SkinnyRx's figure is dose-flat while ShedRx's structure is not.

§ Side by side

§ Each record, read aloud

The two records, condensed

ShedRx: the record, condensed

ShedRx’s tirzepatide program bills $289 a month once every mandatory fee is counted, measured at the 10 mg maintenance basis. The structure is tiered: the advertised entry point is $199, but the maintenance figure — the one a full year is actually billed at — is $289. That $90 gap between the ad and the anniversary is the single most important line in this record.

The absence worth noticing: no mandatory membership. Across this index memberships run $25–$145 a month and hide outside headline prices; here the headline is the bill.

To place the number: #5 of 17 verified programs, with the floor $74/month below at NexLife↗ ($215); the approved-product yardstick (Zepbound (LillyDirect↗)) sits at $449, so the compounded case here is worth $160 a month. A year at this figure: $3,468 monthly-billed.

On semaglutide, the number that matters at ShedRx is $249 a month all-in — the figure at the 2.4 mg maintenance basis this whole site ranks on. The structure is tiered: the advertised entry point is $175, but the maintenance figure — the one a full year is actually billed at — is $249. That $74 gap between the ad and the anniversary is the single most important line in this record.

The absence worth noticing: no mandatory membership. Across this index memberships run $25–$145 a month and hide outside headline prices; here the headline is the bill.

Context for that figure: it ranks #13 of 20 in the verified semaglutide index — $116/month above the floor (Oak Longevity, $133) — and sits $100 under the brand benchmark (Wegovy (NovoCare↗), $349 at maintenance). Annualized, a monthly-billed year here runs $2,988.

Operationally at ShedRx: shipping included; commitment none month-to-month; cancellation 72-hour notice before the next billing cycle; pharmacy not publicly named — ask in writing before paying; states: not published; evidence source-verified, captured 2026-08-05. The full record with source and archive links: the ShedRx page · visit ShedRx ↗

SkinnyRx: the record, condensed

Start with the load-bearing figure: $299 a month, all-in, is what SkinnyRx charges for tirzepatide at the 10 mg basis. Because pricing is flat across the ladder (2.5 → 5 → 7.5 → 10 mg (12.5 and 15 mg available)), a dose increase at SkinnyRx is a clinical event and not a billing one. Whatever your prescriber decides, the invoice does not move, which makes this one of the few programs whose headline figure you can actually plan a year around.

The absence worth noticing: no mandatory membership. Across this index memberships run $25–$145 a month and hide outside headline prices; here the headline is the bill.

To place the number: #7 of 17 verified programs, with the floor $84/month below at NexLife ($215); the approved-product yardstick (Zepbound (LillyDirect)) sits at $449, so the compounded case here is worth $150 a month. A year at this figure: $3,588 monthly-billed.

On semaglutide, the number that matters at SkinnyRx is $199 a month all-in — the figure at the 2.4 mg maintenance basis this whole site ranks on. The price is dose-flat: the standard titration ladder (0.25 → 0.5 → 1.0 → 1.7 → 2.4 mg) is financially invisible here, because the top rung bills exactly what the bottom rung billed. That converts the advertised number from a floor into a ceiling — the strongest single structural feature a program in this category can have.

The absence worth noticing: no mandatory membership. Across this index memberships run $25–$145 a month and hide outside headline prices; here the headline is the bill.

Context for that figure: it ranks #11 of 20 in the verified semaglutide index — $66/month above the floor (Oak Longevity, $133) — and sits $150 under the brand benchmark (Wegovy (NovoCare), $349 at maintenance). Annualized, a monthly-billed year here runs $2,388.

Operationally at SkinnyRx: shipping included; commitment none; cancellation no membership on compounded programs; pharmacy not publicly named — ask in writing before paying; states: not published; evidence source-verified, captured 2026-08-05. The full record with source and archive links: the SkinnyRx page · visit SkinnyRx ↗

Tirzepatide: the duel in full

Put the two tirzepatide figures side by side and hold them there: ShedRx at $289, SkinnyRx at $299 — a $10 monthly spread that compounds to $120 over a maintenance year and $240 over two.

Structure sharpens the gap: SkinnyRx’s figure is dose-flat (2.5 → 5 → 7.5 → 10 mg (12.5 and 15 mg available) all bill the same), while ShedRx’s is not — so SkinnyRx’s number is a ceiling and ShedRx’s advertised entry ($199) is a floor. Comparing a ceiling to a floor flatters the floor; this site compares maintenance to maintenance, which is the table above.

Semaglutide: the duel in full

The semaglutide arithmetic between these two is short: $199 (SkinnyRx) against $249 (ShedRx). $50 a month sounds survivable; $600 a year is a decision.

Structure sharpens the gap: SkinnyRx’s figure is dose-flat (0.25 → 0.5 → 1.0 → 1.7 → 2.4 mg all bill the same), while ShedRx’s is not — so SkinnyRx’s number is a ceiling and ShedRx’s advertised entry ($175) is a floor. Comparing a ceiling to a floor flatters the floor; this site compares maintenance to maintenance, which is the table above.

A way to feel the $10 monthly gap: over a year it funds 0.4 extra months at ShedRx’s own rate — the difference is not decoration, it is medication. Over two years it compounds to $240, which is the horizon at which structural details (prepaid ladders, membership drag, dose-tier repricing) start mattering more than the sticker itself.

Run the same two programs on the committed basis: ShedRx $289/mo month-to-month against SkinnyRx $299/mo month-to-month. The order holds: ShedRx leads on both readings, so plan structure sharpens the verdict here rather than reversing it. Whichever basis fits your commitment level, the upfront totals above are the honest units.

§ The clock, run forward

Three, six, twelve, twenty-four months — best path each way

3 months: ShedRx $867 monthly; SkinnyRx $897 monthly — best path favors ShedRx by $30. 6 months: ShedRx $1,734 monthly; SkinnyRx $1,794 monthly — best path favors ShedRx by $60. 12 months: ShedRx $3,468 monthly; SkinnyRx $3,588 monthly — best path favors ShedRx by $120. 24 months: ShedRx $6,936 monthly; SkinnyRx $7,176 monthly — best path favors ShedRx by $240.

Prepaid paths above are billed upfront and assume the published rate holds (the 24-month figures extend the 12-month rate, an assumption worth naming). The honest reading: over short horizons the monthly gap decides; over long horizons the prepaid ladders and structural traps (dose tiers, memberships) take over — which is exactly the split the verdict section below scores.

The same clock, on semaglutide

3 mo: ShedRx $747 vs SkinnyRx $597 — $150 to SkinnyRx. 6 mo: ShedRx $1,494 vs SkinnyRx $1,194 — $300 to SkinnyRx. 12 mo: ShedRx $2,988 vs SkinnyRx $2,388 — $600 to SkinnyRx. 24 mo: ShedRx $5,976 vs SkinnyRx $4,776 — $1,200 to SkinnyRx.

Same rules as above: prepaid figures are upfront commitments, and the 24-month lines extend the 12-month rate as a stated assumption. Where the two molecules crown different winners between these two programs, that split is itself the finding — molecule choice and provider choice are separate decisions.

§ Structure vs structure

Everything besides the price

Coverage: ShedRx publishes “not published”; SkinnyRx publishes “not published” — for anything short of an explicit 50-state claim, intake is the final word.

Neither names its pharmacy publicly — the single most useful disclosure in this category, missing on both sides; ask each, in writing, before paying either.

Exit terms: ShedRx — none month-to-month; 72-hour notice before the next billing cycle. SkinnyRx — none; no membership on compounded programs.

Evidence: ShedRx source-verified (captured 2026-08-05); SkinnyRx source-verified (2026-08-05).

The pattern worth internalizing: in this market, structural honesty and price honesty travel together. Programs that publish pharmacies and state lists tend to publish real maintenance prices; programs that hide one usually hide the other.

In the full tirzepatide index these two sit at #5 and #7 of 17: between them lie 1 other program, and the whole ladder is at cheapest tirzepatide providers. In the full semaglutide index these two sit at #13 and #11 of 20: between them lie 1 other program, and the whole ladder is at cheapest semaglutide providers.

§ If you move

Switching between ShedRx and SkinnyRx

Prescriptions do not transfer like phone numbers: moving in either direction means completing the destination’s intake and having its prescriber write a new patient-specific prescription. The mechanics that prevent a bad month: confirm the destination serves your state and quotes your current dose in writing before cancelling anything; time the first new shipment to overlap the last old one rather than gap it; cancel the origin per its published terms (ShedRx: 72-hour notice before the next billing cycle; SkinnyRx: no membership on compounded programs) and screenshot the confirmation; and never leave a prepaid balance stranded — which is the standing argument for prepaying only after a program has already earned a few monthly cycles.

§ Verdict by situation

Which one, for whom

§ More pairings